Considerations To Know About EAM-2201

Considerations To Know About EAM-2201

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The intention of this review should be to characterize the metabolites of EAM-2201 in human hepatocytes attained in vitro and those in liver and urine specimens obtained in vivo with the autopsy of an EAM-2201 abuser.

Twelve metabolites of a artificial cannabinoid, EAM-2201, have been tentatively identified in human hepatocytes in vitro, As well as in human liver and urine specimens in vivo for the first time. There was a definite difference in metabolism profile among the in vitro As well as in vivo final results.

EAM-2201 was incubated with human hepatocytes for 3 h in a very CO2 incubator and the metabolites of EAM-2201 were generated. The human liver specimen was homogenized as well as the metabolites ended up extracted. The urine specimen was hydrolyzed initial with β-glucuronidase along with the metabolites ended up extracted.

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